Which NAD+ Brands Actually Work? Let Me Reveal My Top 5 NAD+ Providers To Outperform The Visible Aging Process
Skincare topicals and injectables like Botox only treat the skin surface.
NAD+ provides visible anti-aging results by working at the cellular level.
So if you’re worried about losing skin elasticity and collagen levels falling (causing you to look years older than you are!) using NAD+ to deliver peptides into the skin will help you look & feel younger beyond age 30 by:
- Accelerating healthy skin cell renewal
- Aiding DNA Repair
- Supporting metabolic turnover
- Enhancing deep sleep
Every cell in your body contains NAD+, which is a powerful coenzyme that helps fuel cellular energy and support healthy aging.
By your mid-30s, your body’s NAD⁺ levels can fall by up to 50%.
That's why using NAD+ injections are so essential for healthier, younger-looking skin:
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Injections have a higher bioavailability than other alternative NAD methods (patches, creams, pills, etc.) because they support faster NAD+ uptake in the bloodstream so you see results in days, not months.
- Visible wrinkles and fine lines (caused by low collagen levels in the bloodstream)
- Slower skin regeneration & hair follicle turnover (also known as "balding")
- Higher stress levels + poorer immune system function
In-clinic NAD+ IV drips are effective for anti-aging, but they can cost thousands of dollars per month!
Fortunately, as a medical researcher with over two decades of lab-work experience at my clinic in New York, I've found 5 top NAD+ brands you can use at home that actually work at a cellular level.
Here are 5 of my favorite NAD+ brands that can help provide long-term support against premature cellular decline:
- Cost: Lowest entry price for at-home NAD+ injections on this list!
- Clinically-tested formula: Supports cellular health by recycling NAD+ to increase NAMPT
- Inflammation support: Helps reduce systemic stress linked to fatigue
- Sleep & rhythm: Supports circadian balance and muscle recovery
- Accessibility: No insurance, no clinic visits, no long approval process
- Support: Unlimited access to a team of board-certified clinicians
- Only available online
Why Palm Beach Labs Is #1:
As a researcher with more than a decade and a half of experience, I want to see my readers reach their goals by putting their hard-earned money toward treatments that actually work.
And this brand?
In my opinion, Palm Beach Labs may be the only NAD+ provider you (or I) will ever need again, period!
And I'm not the only one, just check out some of these before/afters from a few patients I've spoken with who had skin glow-ups:
I was originally introduced to Palm Beach Labs earlier this year after reading a research paper from the National Library of Medicine that discussed optimization of the mitochondria. That journal entry I read mentioned this brand by name.
I’d never seen a private NAD+ supplier mentioned so frequently in an academic journal before, so when I learned how much confidence they had in Palm Beach Lab's formula, I decided I had to try it...
Since my first time using this brand, I’ve never looked back!
I’ve been a Palm Beach Labs patient for the last 6 months and the results have been insane!
For a woman that's 56, I feel like my skin is absolutely glowing, with practically no visible wrinkles:
Here's Why Palm Beach Labs Gets the Top Spot, (In Plain English):
Firstly, there’s the convenience.
Palm Beach Labs offers at-home NAD+ injections with no clinic visits, long appointments, or commutes across town. This is one of the only services that offer this.
Second, there’s the formula. Palm Beach Labs doesn’t just supply NAD+.
This brand supports the body’s ability to recycle it efficiently by increasing NAMPT, a key enzyme involved in NAD regeneration.
Most NAD+ brands focus on adding more to their formula.
Palm Beach Labs treatments support NAD+ levels and helping your body recycle NAD+ efficiently (NAMPT) so you can enjoy consistent, sustained support for your body + skin, not just short term results.
Then there’s inflammation control. By restoring NAD+ levels alongside NAMPT, Palm Beach Labs helps lower systemic inflammation, one of the biggest drivers of fatigue and stress (both of which can have a serious affect on appearance!)
Plus, Palm Beach Labs makes NAD+ accessible to anyone who needs it, with:
- No pre-existing medical condition required
- No insurance needed
- No clinic visits or long eligibility delays
- It’s also more affordable than any other provider on the market, costing you less than a cup of coffee a day.
- And signing up is easy too!
I just cannot fault Palm Beach Labs
There are no complicated dosages. No unnecessary add-ons. Just targeted NAD+ support, with 24/7 access to a team of board-certified clinicians to guide you throughout the process.
My energy levels are now so constant, I look like I'm in my 20s again!
And my circadian rhythm is so fine tuned that I sleep like a rock every night.
That’s why Palm Beach Labs has become my go-to recommendation for anyone looking to improve their appearance, as well as their energy levels and overall cellular health with NAD+.
#2 Nura Peptide
Runner-Up Pick (Strong Results, Slower + More Expensive)
- High-grade formulation: High-grade NAD+ formulations enhanced with peptides targeting anti-aging and skin protection.
- Mood + energy + sleep: Supports mood, energy levels, and sleep quality alongside aesthetic benefits.
- Medical team: Strong medical team offering one-on-one guidance and flexible dosage adjustments.
- Brand trust: Cult-favorite brand with a loyal user base and proven long-term results.
- Delays: Requires sign-up and approval process, causing delays before starting treatment.
- Shipping: Shipping can take over a week, even for domestic U.S. orders.
- Cost: Significantly more expensive than most competitors, often exceeding $300 per month.
- Less immediate access: Less immediate access compared to faster, more streamlined NAD+ providers like Palm Beach Labs.
Nura Peptide (Full Notes):
Nura Peptide is my second pick.
This is another huge brand that’s made it incredibly easy for the general public to access NAD+ from home.
They’re a provider that has built up a cult-favorite following that love the long-term results in anti-aging and skin protection. Just like Palm Beach Labs, their NAD+ packages are formulated with high-grade peptides that target key concerns like fine lines, dull mood, low energy and poor sleep. And just like my top pick, Nura Peptide did an amazing job, giving my skin a noticeable glow within a few days of use. The radiance-boosting effect was both immediate and lasting, with an impressive plumping and smoothing action that made my skin look healthier and more vibrant overall.
What really sets this provider apart is their medical team: all of whom help you navigate your treatments easily, talk to you one-to-one so you can adjust or up the dosage.
Tradeoffs to know before you choose this:
My only gripes with this brand are their prices and service.
Firstly, you have to sign up for their service and wait around for a few days before you hear back. Already, that means you lose a few days even if they approve you in less than 5 minutes of looking at your application. Plus, I had to wait for more than a week for my NAD+ to arrive at my apartment (I live in New York, so it’s typical that I get all my mail in less than five days, especially considering it’s domestic US shipping.)
Secondly, their service is significantly more expensive than other providers, costing upwards of $300 per month depending on the package you choose.
So overall, Palm Beach Labs still holds an edge for its NAD+ service and dosage plans. But Nura remains a gold standard NAD+ provider, especially for those looking for a no-nonsense formula that can deliver results when you need them, just expect to wait a while longer and pay more out of pocket.
#3 Eden
Strong Platform + Support, But Forced Dose Ramp Can Slow Momentum
- Track record: Established, well-trusted brand with a strong track record since the early 2020s.
- Portal: User-friendly online portal that makes managing, changing, or canceling subscriptions easy.
- Payment options: Offers flexible payment options, including Buy Now, Pay Later services like Klarna and Afterpay.
- Mandatory low-dose start: Mandatory low-dose starting protocol, regardless of prior experience with NAD+ or peptide therapies.
- Slow escalation: Gradual dose escalation can delay visible or noticeable results for months.
- Cost: Ongoing subscription costs are relatively high, starting around $190 per month.
Eden (Full Notes):
In my third place spot, I’ve selected Eden.
This is another tried-and-true classic in the world of NAD+ peptides. Since its introduction in the 2020s, this has become another well-loved brand that has helped thousands of patients access high quality, clinically-tested peptides to target fine lines, wrinkles, and uneven skin tone.
Just like my top 2 picks, this is another brand that takes their NAD+ formulation, as well as their medical advice, very seriously. Their clinical team will guide you through every step of the way, and they’ll give you a direct line to your own personally allocated MD if you have any questions about dosage, usage etc.
Additionally, their online portal works great so if you want to change or cancel your subscription it’s easy to do at a moment’s notice.
I must say though, I generally prefer when telehealth companies let you select your own initial starting point if you have the same sort of medicine or treatment before. Unfortunately using Eden means that you will have to start with the smallest dose possible and then move up to the largest, regardless of your own experience. So that often means that patients can go months without ever seeing any real results, all while they’re still spending upwards of $180 per month on subscription fees!
Although costs are fairly high with this brand, it’s also worthwhile to mention that they offer Buy Now Pay Later schemes like Klarna and Afterpay–so if money is tight you could opt to use those services to fund your NAD+ journey. However, as a researcher as well as a consumer, I’d advise against using these schemes if you can since costs can add up so quickly over time.
#4 Ageless RX
Most Versatile Formats (Injectable + Non-Injectable), Premium Pricing
- Track record: Established, well-trusted brand with a strong track record since the early 2020s.
- Beginner-friendly formats: Ideal for beginners or those who prefer lower-dose or non-injectable NAD+ therapies.
- Evaluation included: Free medical evaluation included during sign-up.
- Reputation: Gold-standard reputation in the NAD+ space with medically supervised care.
- Cost: Most expensive brand on the list, with injectables starting around $235 per month.
- Total spend: High overall treatment costs, often exceeding $1,000 over a few months.
- Long-term value: Less cost-effective for users committed to long-term NAD+ therapy.
- Pricing barrier: Premium pricing may be prohibitive compared to similarly effective providers.
Ageless RX (Full Notes):
In my fourth place spot, I’ve selected Ageless RX.
In all honesty, I only have one main gripe with this brand: it’s the most expensive on this list and one of the most costly NAD+ brands out there, with injectables starting at around $235 per month.
However (and this is a huge however) AgelessRx is one of the most versatile NAD+ brands online.
If injectables aren’t for you, or you’d prefer to start with a lower dose, you have the option of using Ageless Rx’s unique range of NAD+ creams, patches and nasal sprays.
When you sign up through their medical portal, you get a free medical evaluation. And if you find that the NAD+ method you’re using isn’t for you, or you’d just like to lower your dosage, their handy app lets you switch between these treatment methods as you see fit.
It’s a gold standard NAD+ brand, but it loses major points on high costs that will cost users a minimum of $1000 for a few months of treatment.
#5 RegenMD
Trustworthy Purity Signals, But Slow + Rigid + Less Transparent
- Established brand: Established brand in the regenerative and hormone wellness space.
- Pharmacy production: Pharmaceutical-grade NAD+ injectables produced in FDA-registered compounding pharmacies.
- Purity: Solid, reliable formulation with verified purity standards.
- Not beginner-friendly: Not beginner-friendly compared to newer NAD+ telehealth providers.
- Slow onboarding: Slow, dated onboarding process with lengthy medical intake and approval steps.
- Wait times: Long wait times before starting treatment, often exceeding two weeks.
- Value vs clinic: Nearly as expensive as in-clinic NAD+ therapy without equivalent hands-on support.
- Rigid plans: Rigid treatment plans that limit flexibility for both new and experienced users.
- Low start dose: Lower starting doses can delay noticeable results while monthly billing continues.
RegenMD (Full Notes):
In my fifth and final spot, I’ve selected RegenMD.
RegenMD is a well-known name in the regenerative and hormone wellness space, and they’ve been around long enough to earn a degree of trust, especially among users already familiar with peptide therapy or NAD+ injections.
Their NAD+ injectable is pharmaceutical grade, produced in FDA-registered compounding pharmacies, and from a purity standpoint, it does exactly what it claims to do. The formulation itself is solid, and users who stick with it long enough often report improvements in baseline energy and recovery. That said, RegenMD is not a beginner-friendly option, and that’s ultimately why it lands at the bottom of my list.
Unlike Palm Beach Labs or Nura, RegenMD does not prioritize speed or accessibility. The onboarding process is slower, more clinical, and feels dated compared to newer telehealth platforms. You’ll need to complete a full medical intake, wait for approval, and then wait again for shipping, often stretching the process to 2+ weeks before you even begin treatment.
Next, there’s the lack of pricing transparency.
RegenMD’s NAD+ pricing isn’t clearly laid out upfront, and by the time prescriptions, consultations, and follow-ups are factored in, monthly costs can climb quickly, sometimes as high as $210. For many users, this ends up being nearly as expensive as in-clinic NAD+ therapy, without offering the same level of hands-on support.
Another concern I uncovered during my review is rigidity in treatment plans.
For experienced NAD+ users, this can feel unnecessarily restrictive. And for beginners, it often results in lower starting doses that delay noticeable results, all while the monthly billing continues.
Either way, it’s well placed at number 5 on this list, but if you’re eager to get going on your NAD+ journey today, there are better, more affordable options out there.